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In relation to chronic studies, increased VO 2peak (11, 16) and decreased respiratory quotients (12, 32) have been presented, while many groups have reported no differences (3, 5, 6, 10, 13, 18, 23, 30)

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Multi-omics models and the integration of multi-dimensional datasets comprising nutritional genomics, phenotypes and lifestyles are paramount to understand the metabolic variability between individuals and achieve personalized guidance for tailored polyphenol-based immunonutritional plans

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Table 2 Human studies on L-carnitine supplementation in MASLD